Impact of CYP19A1 and ESR1 variants on early-onset side effects during combined endocrine therapy in the TEXT trial. Breast Cancer Research

Harriet Johansson1, Kathryn P. Gray2, Olivia Pagani3,4,5, Meredith M. Regan6, Giuseppe Viale7, Valentina Aristarco1, Debora Macis1, Antonella Puccio1, Susanne Roux8, Rudolf Maibach8, Marco Colleoni1, Manuela Rabaglio9, Karen N. Price9,10, Alan S. Coates11, Richard D. Gelber12, Aron Goldhirsch13, Roswitha Kammler14, Bernardo Bonanni1†, Barbara A. Walley15,16† and the TEXT principal investigators 1Division of Cancer Prevention and Genetics, […]

RAS testing practices and RAS mutation prevalence among patients with metastatic colorectal cancer: results from a Europe-wide survey of pathology centres. BMC Cancer

Annemarie Boleij1, Véronique Tack2, Aliki Taylor3, George Kafatos3, Sophie Jenkins-Anderson4, Lien Tembuyser2, Els Dequeker2 and J. Han van Krieken1 1Department of Pathology, Radboud University Medical Centre 2Department of Public Health and Primary Care, University of Leuven 3Centre for Observational Research, Amgen Ltd 4Adelphi Research (Global) Abstract: Background Treatment options for patients with metastatic colorectal cancer […]

Degradation Rate of 5-Fluorouracil in Metastatic Colorectal Cancer: A New Predictive Outcome Biomarker? PLOS One

Andrea Botticelli1, Marina Borro2, Concetta Elisa Onesti3, Lidia Strigari4, Giovanna Gentile5, Bruna Cerbelli6, Adriana Romiti1, Mario Occhipinti3, Claudia Sebastiani5, Luana Lionetto5, Luca Marchetti7, Maurizio Simmaco2, Paolo Marchetti1,3,5, Federica Mazzuca1,3 1Department of Clinical and Molecular Medicine, “Sapienza” University of Rome, Rome, Italy 2Department of Neurosciences, Mental Health and Sensory Organs (NESMOS), “Sapienza” University of Rome, Rome, […]

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