SNPs in DNA repair or oxidative stress genes and late subcutaneous fibrosis in patients following single shot partial breast irradiation. Journal of Experimental & Clinical Cancer Research
Elisabetta Falvo1, Lidia Strigari2, Gennaro Citro1, Carolina Giordano3, Genoveva Boboc3, Fabiana Fabretti3, Vicente Bruzzaniti2, Luca Bellesi2, Paola Muti4,5, Giovanni Blandino6 and Paola Pinnarò3 1Laboratory of Pharmacokinetic/Pharmacogenomic, Regina Elena National Cancer Institute 2Laboratory of Medical Physics and Expert Systems, Regina Elena National Cancer Institute 3Department of Radiation Oncology, Regina Elena National Cancer Institute 4Department of Oncology […]
Investigation of MTHFR, DPYD, and TSER polymorphisms in 5-FU toxicity: a case report
5-Fluorouracil (5-FU) is a chemotherapic drug belonging to the fluoropyrimidine family, broadly used either alone or in combination with other agents. 5-FU indications include palliative and adjuvant treatment of many cancers, including colorectal, breast, head and neck cancers. 5-FU requires enzymatic conversion to the nucleotide floxouridine monophosphate (FdUMP) in order to exert its cytotoxic activity. […]
HPV in exhaled breath condensate of lung cancer patients. British Journal of Cancer
G E Carpagnano1, A Koutelou1, M I Natalicchio2, D Martinelli3, C Ruggieri1, A Di Taranto1, R Antonetti1, F Carpagnano4 and M P Foschino-Barbaro1 1Institute of Respiratory Disease, Department of Medical and Occupational Sciences, Faculty of Medicine, University of Foggia, Foggia, Italy 2III Laboratory of Analysis, Department of Clinical Pathology, Riuniti Hospital Foggia, Foggia, Italy 3Department […]
Stefania Marzinotto, Francesca Sessa, Alessandra Franzoni,“KRAS Codons 12 and 13 Mutation Analysis: A Comparative Study between Direct Sequencing and a New Sensitive Real-Time PCR Assay,” Sequencing, vol. 2011, Article ID 895709, 7 pages, 2011. doi:10.1155/2011/895709
Dose and polymorphic genes xrcc1, xrcc3, gst play a role in the risk of developing erythema in breast cancer patients following single shot partial breast irradiation after conservative surgery. BMC Cancer
Elisabetta Falvo1, Lidia Strigari2, Gennaro Citro1, Carolina Giordano3, Stefano Arcangeli3, Antonella Soriani2, Daniela D’Alessio2, Paola Muti4, Giovanni Blandino5, Isabella Sperduti4 and Paola Pinnarò3 1Laboratory of Pharmacokinetic/Pharmacogenomic, Regina Elena National Cancer Institute 2Laboratory of Medical Physics and Expert Systems, Regina Elena National Cancer Institute 3Department of Radiation Oncology, Regina Elena National Cancer Institute 4Scientiphic Direction, Regina […]
The pyrosequencing experience: testing colorectal cancer patients for KRAS status in the clinical practice
Testing KRAS status in advanced colorectal cancers has gained a practice-changing level of evidence, being predictive of resistance to the point of rendering the use of EGFR-inhibitors useless in patients carrying KRAS mutations. Since there is noagreement on the best testing method, different assays are commonly used in the clinical practice to determinate KRAS status. […]