Storage Time and DNA Quality Determine BRCA1/2 Sequencing Success in Prostate Cancer: A Multicentre Analysis with Therapeutic Implications
Shooting Cancer Highlights – UGT1A1 & DPYD: Safer chemotherapy starts with genotyping
DPYD Genotyping in Fluoropyrimidine Therapy: Reducing Toxicity, Improving Outcome Fluoropyrimidines such as 5-fluorouracil (5-FU), capecitabine, and tegafur are widely used in oncology, treating over 3.5 million patients annually—with 600,000 in Europe alone. Despite their effectiveness, these drugs carry a significant risk of toxicity: 10–40% of patients develop severe side effects (Grade 3–4) requiring hospitalisation and […]