Giovanna Elisiana Carpagnano et al., HPV in exhaled breath condensate of lung cancer patients. British Journal of Cancer

G E Carpagnano1, A Koutelou1, M I Natalicchio2, D Martinelli3, C Ruggieri1, A Di Taranto1, R Antonetti1, F Carpagnano4 and M P Foschino-Barbaro1

1Institute of Respiratory Disease, Department of Medical and Occupational Sciences, Faculty of Medicine, University of Foggia, Foggia, Italy
2III Laboratory of Analysis, Department of Clinical Pathology, Riuniti Hospital Foggia, Foggia, Italy
3Department of Medical Sciences, Section of Hygiene, Faculty of Medicine, University of Foggia, Apulia Regional Epidemiological Observatory, Foggia, Italy
4Department of Thoracic Surgery, Case di Cura Riunite, La Madonnina, Bari, Italy

Abstract

background: A recent intriguing carcinogenetic hypothesis for lung cancer foresees its viral aetiology. The human papilloma virus (HPV) is the main virus actually recognised in the pathogenesis of lung cancer. The aim of this study was to investigate, for the first time to our knowledge, the presence of HPV in the exhaled breath condensate (EBC) of lung cancer patients.